This workshop introduces crmPack as an R framework for model-based dose escalation trial design. Participants explore how its unified, object-oriented approach can support design and simulation work without starting from a new implementation for every study. Hands-on examples illustrate the package’s use and provide a starting point for applying it to future dose escalation projects. The session places the software in the context of more informative and efficient early-phase trial designs, while helping participants understand how a reusable open-source framework can make these methods more accessible. The emphasis is on practical introduction and application rather than software development from scratch.